Contact your doctor immediately if you experience any of the following:
- Suicidal thoughts or behaviors Severe anxiety or panic attacks Unusual changes in mood, such as extreme sadness or irritability Hallucinations or delusions Difficulty concentrating or making decisions Significant changes in sleep patterns, including insomnia or excessive sleepiness Unexplained weight loss or gain Rapid heart rate or palpitations Seizures Severe headaches Persistent nausea or vomiting Difficulty urinating
Medication Interactions
Inform your physician about all medications, supplements, and herbal remedies you are taking. Certain substances can interact negatively with Effexor XR, potentially increasing the risk of side effects or reducing its effectiveness. This includes, but isn’t limited to, MAO inhibitors, other antidepressants, and St. John’s Wort.
Dosage Adjustments and Discontinuation
Never adjust your dosage without consulting your doctor. Sudden changes can lead to serious withdrawal symptoms. Your doctor should supervise any gradual reduction in your dosage to minimize withdrawal effects. Discuss any concerns about your medication with your healthcare provider before stopping the treatment.
Ongoing Monitoring
Regular check-ups with your doctor are critical to monitor your response to Effexor XR and adjust your treatment plan as needed. This includes regular blood pressure and heart rate checks.
Specific Symptoms Warranting Immediate Attention
Seek immediate medical attention if you experience symptoms suggesting serotonin syndrome, such as high fever, muscle rigidity, rapid heart rate, and confusion.


