Check the medication’s appearance carefully. Discoloration is a major red flag.
Color Changes
- Expect amoxicillin capsules to be consistent in color. Significant changes, like darkening or fading, indicate potential degradation. Powdered amoxicillin should maintain its original hue. Any shift in color suggests the drug might no longer be effective. Liquid amoxicillin may show cloudiness or sediment that wasn’t present originally. This is a strong sign of spoilage.
Tablet Integrity
- Examine tablets for cracks, chipping, or crumbling. These signs show physical degradation, possibly affecting potency. Unusual stickiness or clumping in tablets or powder points to moisture damage and should raise concerns.
Smell and Taste
A change in smell or taste is another key indicator. Amoxicillin shouldn’t have a strong, unpleasant odor. A sour, musty, or generally off-putting smell means it’s likely expired.
Other Physical Signs
Check the packaging. Significant damage (tears, punctures) may compromise the medicine’s integrity. Inspect the bottle/container. Observe if it’s swollen or leaking; this indicates potential damage and spoilage.
Important Note:
These visual clues offer guidance; they are not substitutes for checking the expiration date. Always prioritize the printed expiration date. If you’re unsure about the amoxicillin’s condition, dispose of it properly and consult your pharmacist or doctor.


