Understanding Viagra’s Mechanism of Action

Viagra, or sildenafil, primarily works by inhibiting an enzyme called phosphodiesterase-5 (PDE5). This enzyme normally breaks down a chemical messenger called cyclic guanosine monophosphate (cGMP). Higher cGMP levels relax the smooth muscles in the blood vessels of the penis, increasing blood flow.

Increased Blood Flow and Erection

By blocking PDE5, Viagra allows cGMP levels to remain elevated for longer. This sustained increase in cGMP promotes vasodilation, leading to improved blood flow into the corpus cavernosum – the spongy tissue within the penis responsible for erections. This increased blood flow facilitates a firmer and longer-lasting erection.

Dosage Considerations

The dosage of Viagra, whether 50mg or 100mg, depends on individual factors and should always be determined by a physician. A higher dosage doesn’t necessarily mean a better outcome; it may increase the risk of side effects. Your doctor will consider your health history, current medications, and the desired therapeutic effect when recommending a suitable dose. Always follow their instructions precisely.