Viagra (sildenafil) and Cialis (tadalafil) both treat erectile dysfunction, but they work slightly differently. Viagra inhibits PDE5, an enzyme that breaks down cGMP, a crucial molecule for achieving and maintaining an erection. Increased cGMP levels lead to relaxed blood vessels in the penis, allowing increased blood flow.
Viagra’s Action
Viagra’s effect is relatively short-lived, typically lasting 4-5 hours. Its onset is faster than Cialis. This makes it suitable for situations where predictable timing is needed.
Cialis’s Action
Cialis, also a PDE5 inhibitor, shares a similar mechanism, but its effects are much longer lasting – up to 36 hours. This longer duration is due to its different metabolic properties. This extended effect allows for more spontaneous intimacy.
Key Differences Summarized
The primary difference lies in duration of action: Viagra provides a shorter, more targeted effect, while Cialis offers a longer-lasting effect, sometimes called the “weekend pill”. Consult a doctor to determine which medication best suits your individual needs and health profile. Both require a prescription.
