Diane-35 contains two active ingredients: cyproterone acetate and ethinylestradiol. Cyproterone acetate is a potent antiandrogen, meaning it blocks the effects of male hormones (androgens) like testosterone. Ethinylestradiol is a synthetic estrogen that works alongside cyproterone acetate to regulate the menstrual cycle.
Cyproterone Acetate’s Role
Cyproterone acetate binds to androgen receptors, preventing androgens from binding and exerting their effects. This action is key to its use in managing conditions like acne and hirsutism (excessive hair growth) caused by high androgen levels. Specifically, it reduces sebum production (oil from the skin glands), which contributes to acne, and inhibits hair follicle growth, thus reducing unwanted hair.
Ethinylestradiol’s Contribution
Ethinylestradiol’s role is multifaceted. Primarily, it works with cyproterone acetate to suppress ovulation, preventing pregnancy. Furthermore, it helps regulate the menstrual cycle, reducing irregularities and often improving acne and hirsutism further by modulating hormone balance.
Mechanism of Action Summary
- Androgen Blockade: Cyproterone acetate blocks androgen receptors, lowering androgen activity. Ovulation Suppression: Ethinylestradiol, in combination with cyproterone acetate, prevents the release of an egg, thereby preventing conception. Hormonal Regulation: Both components work together to balance hormone levels, improving symptoms related to androgen excess.
Points to Note:
This is a simplified explanation. The exact mechanisms involved are complex and involve multiple interactions within the endocrine system. Always consult your doctor or pharmacist for detailed information and advice concerning Diane-35. Individual responses to Diane-35 vary. Side effects are possible and should be reported to your healthcare provider immediately.
