Clomid, or clomiphene citrate, stimulates your pituitary gland to release more follicle-stimulating hormone (FSH) and luteinizing hormone (LH). These hormones prompt your ovaries to develop and release multiple eggs, increasing your chances of conception. This is crucial for individuals experiencing anovulation, the absence of ovulation.
How Clomid works: Clomid acts as a selective estrogen receptor modulator (SERM). It blocks estrogen receptors in the hypothalamus, tricking your brain into thinking estrogen levels are low. This triggers the release of GnRH, a hormone that subsequently stimulates FSH and LH production. Consequently, multiple follicles mature, increasing the likelihood of multiple eggs being released during ovulation.
Important Note: Clomid doesn’t guarantee ovulation. Success rates vary depending on individual factors like age and underlying fertility issues. Your doctor will monitor your response through blood tests and ultrasounds to ensure optimal follicle development and avoid ovarian hyperstimulation syndrome (OHSS), a serious complication.
Monitoring Ovulation: Your doctor will likely recommend tracking your ovulation using blood tests to measure hormone levels and/or ultrasound scans to visualize follicle growth and the release of eggs. Tracking basal body temperature or using ovulation predictor kits (OPKs) may also be useful, but these methods are less accurate than medical monitoring.
Dosage and Treatment Cycles: Your doctor determines the appropriate Clomid dosage and treatment duration. Typical dosages range from 50mg to 150mg daily for 5 days, typically starting on cycle day 3, 5 or 7. Multiple treatment cycles may be necessary. Strict adherence to your doctor’s instructions is vital.
Side effects: Common side effects include hot flashes, mood swings, bloating, and headaches. Less frequent, but potentially serious, side effects include ovarian hyperstimulation syndrome (OHSS) and multiple pregnancies. Report any concerning symptoms to your healthcare provider immediately.


