Always consult your doctor before combining Advil (ibuprofen) and prednisone. They will determine the appropriate dosages based on your individual health needs and any other medications you are taking. Never adjust your prescribed dosages without medical supervision.
Ibuprofen Dosage Adjustments
Your doctor might recommend a lower ibuprofen dose than usual while taking prednisone. Prednisone can increase the risk of stomach ulcers and bleeding, and ibuprofen also carries this risk. Combining them increases this risk significantly. Closely monitor for any signs of gastrointestinal distress.
Prednisone Tapering
Prednisone is typically tapered gradually, rather than stopped abruptly, to minimize withdrawal symptoms. Your doctor will provide a specific tapering schedule. Following this schedule carefully is crucial. Never stop prednisone suddenly without medical guidance.
Timing of Medication
Taking ibuprofen and prednisone at different times of the day might help minimize potential side effects. Your doctor will advise on the best timing for your specific situation. For example, taking ibuprofen with food may reduce stomach irritation.
Monitoring Side Effects
Pay close attention to any side effects experienced when taking both medications. Report any unusual symptoms, such as stomach pain, black or bloody stools, or unusual bruising, immediately to your doctor. Regular check-ups during concurrent use are beneficial.


