If you suspect a Promethazine with codeine overdose, act quickly. Immediate medical help is crucial.
Look for these warning signs: extreme drowsiness or sleepiness that’s difficult to wake from; slow, shallow breathing; a weak or rapid pulse; cold, clammy skin; confusion; seizures; coma; blue-tinged fingernails or lips (cyanosis); and pinpoint pupils.
Don’t hesitate. Call emergency services immediately (911 in the US). While waiting for help:
| Check breathing | Ensure the person is breathing. If not, begin CPR. |
| Maintain airway | Turn the person on their side to prevent choking. |
| Monitor vital signs | Observe breathing rate, heart rate, and level of consciousness. |
| Provide information | Give emergency responders details about the medication ingested and the amount. |
Time is of the essence. Prompt medical intervention significantly improves the chances of a positive outcome. Do not attempt to treat the overdose yourself. Trust medical professionals to provide the necessary care.


