Choose Propranolol CR (controlled-release) if you need a twice-daily dosage for consistent blood pressure management. Opt for Propranolol ER (extended-release) for once-daily convenience, prioritizing a smoother, more predictable medication level throughout the day.
Key Differences in Release Profiles
- Propranolol CR: Delivers medication in a controlled manner over approximately 8-12 hours, requiring twice-daily administration. Propranolol ER: Provides sustained release over a 24-hour period, requiring only one daily dose.
This difference in release profiles directly impacts medication levels in the bloodstream. Propranolol CR produces a more even medication level within each 12-hour period. Propranolol ER aims for a consistent level throughout the entire 24-hour cycle. The optimal choice depends on individual needs and physician recommendations.
Considerations for Patient Selection
Dosage Frequency Preference: Patients preferring a twice-daily regimen might find Propranolol CR more suitable. Those seeking once-daily convenience might opt for Propranolol ER. Individual Metabolism: How your body processes medication influences the choice. A doctor considers metabolic rate when deciding which formulation is better suited for you. Specific Health Conditions: Certain conditions might necessitate one formulation over the other. For example, for managing performance anxiety, a faster-acting release might be preferred.
Always consult your doctor before switching between Propranolol CR and ER or changing your dosage. They can assess your specific needs and determine the most appropriate medication and schedule to manage your condition effectively.
Potential Side Effects
Both formulations share similar potential side effects including dizziness, fatigue, nausea, and low blood pressure. However, the frequency and severity can vary slightly depending on the release profile and individual patient response. Open communication with your doctor about any experienced side effects is crucial for medication management.


