Prednisone, a corticosteroid, is the cornerstone of Polymyalgia Rheumatica (PMR) treatment. It rapidly reduces inflammation and improves symptoms like pain and stiffness. Doctors typically prescribe a relatively high dose initially, often 15-20mg daily, to achieve quick symptom relief.
Dosage and Tapering
The initial high dose isn’t maintained indefinitely. The goal is to gradually reduce (taper) the prednisone dosage over several months. This tapering schedule is individualized, depending on your response to treatment and overall health. A too-rapid decrease can cause a return of symptoms; a too-slow decrease prolongs exposure to potential side effects.
Managing Side Effects
Prednisone can cause various side effects, including weight gain, increased blood sugar, high blood pressure, and osteoporosis. Your doctor will monitor you closely for these, and a plan to mitigate them may involve lifestyle adjustments (diet, exercise) and/or other medications.
Alternative and Adjunctive Treatments
While prednisone is highly effective, some individuals may benefit from combining it with other therapies. For example, low-dose methotrexate can help reduce the overall prednisone dose needed. Physical therapy assists with maintaining mobility and strength, lessening reliance on prednisone in the long run. Regular exercise also plays an important role in improving overall health.
Long-Term Outlook
Most patients achieve remission with prednisone, but maintenance therapy may be needed in some cases. Close collaboration with your rheumatologist is vital to establish an optimal treatment strategy and minimize long-term side effects, ensuring the best possible quality of life.
Important Note:
This information is for general knowledge and does not constitute medical advice. Always consult your doctor for diagnosis and treatment of PMR.


