Metformin, while highly effective for many with PCOS, can cause side effects. The most common are gastrointestinal issues: nausea, diarrhea, bloating, and gas. These usually lessen as your body adjusts to the medication, often within a few weeks. However, if these persist or worsen, contact your doctor.
Managing Gastrointestinal Side Effects
To minimize gastrointestinal discomfort, take Metformin with food, preferably a meal rather than a snack. Start with a low dose and gradually increase it as directed by your physician. Consider splitting your daily dose into smaller portions throughout the day. If you experience severe or persistent diarrhea, dehydration can quickly become a concern; consult your doctor immediately.
Other Potential Side Effects and Precautions
Less frequent, but still possible, side effects include a metallic taste in the mouth, vitamin B12 deficiency (requiring regular monitoring), and lactic acidosis (rare but serious; immediate medical attention is necessary if symptoms like muscle weakness, fatigue, or difficulty breathing develop).
Before starting Metformin, inform your doctor of all existing health conditions, particularly kidney or liver problems, and any other medications you are taking. Regular blood tests are recommended to monitor kidney function and vitamin B12 levels. Always follow your doctor’s instructions regarding dosage and timing.
| Gastrointestinal issues (nausea, diarrhea, bloating, gas) | Common | Take with food; consider smaller doses; contact doctor if persistent |
| Metallic taste | Less common | Report to doctor; may resolve over time |
| Vitamin B12 deficiency | Possible | Regular blood tests required |
| Lactic acidosis | Rare | Seek immediate medical attention |
Alcohol and Metformin
Avoid excessive alcohol consumption while taking Metformin, as this increases the risk of lactic acidosis.
