Azithromycin, while generally well-tolerated, can cause side effects. Common ones include nausea, diarrhea, and abdominal pain. Less frequent but still possible are vomiting, headache, and dizziness. Rarely, more serious reactions like allergic reactions (rash, swelling, difficulty breathing), liver problems (jaundice, dark urine), and heart rhythm abnormalities can occur. Report any concerning symptoms to your doctor immediately.
Several medications interact with azithromycin. Concomitant use with certain drugs can increase the risk of side effects or reduce the effectiveness of either medication. This includes drugs that prolong the QT interval (like some antiarrhythmics and antidepressants), ergot alkaloids, and some anticoagulants. Always inform your doctor and pharmacist of all medications, supplements, and herbal remedies you are taking to avoid potential drug interactions. This includes over-the-counter medications.
Pregnancy and breastfeeding should be discussed with your doctor before starting azithromycin, as its safety in these contexts hasn’t been fully established. Your physician can evaluate the potential risks and benefits.
This information does not replace professional medical advice. Consult your healthcare provider for personalized guidance.


