Always inform your doctor about all medications you are taking, including over-the-counter drugs, herbal supplements, and vitamins, before starting sildenafil. This includes nitrates, often used to treat chest pain. Combining sildenafil and nitrates can cause a dangerous drop in blood pressure.
Alpha-blockers, frequently prescribed for high blood pressure or prostate problems, can also interact with sildenafil, potentially leading to dizziness or fainting. Your doctor might adjust your dosage or recommend alternative treatments.
Some antifungal medications, like ketoconazole and itraconazole, can increase sildenafil levels in your blood, potentially increasing side effects. Similarly, protease inhibitors used for HIV treatment can have a similar effect.
Specific concerns regarding interactions exist with certain medications; always consult your physician for personalized guidance. Do not take sildenafil with riociguat (Adempas), a drug for pulmonary hypertension, as this combination can cause serious side effects.
Remember: This information is not exhaustive. A complete list of potential drug interactions is beyond the scope of this section. Open communication with your healthcare provider is paramount for safe and effective medication management.


