Furosemide’s effect can be significantly altered by other medications. Always inform your doctor about all medications you are taking, including over-the-counter drugs and supplements.
Certain medications can increase furosemide’s effect, potentially leading to excessive fluid loss and electrolyte imbalances. These include:
| Aminoglycoside antibiotics | Gentamicin, Tobramycin | Increased risk of ototoxicity (hearing damage) and nephrotoxicity (kidney damage) |
| Lithium | Lithium carbonate | Increased risk of lithium toxicity; requires close monitoring of lithium levels |
| NSAIDs | Ibuprofen, Naproxen | Reduced furosemide effectiveness; monitor blood pressure and fluid balance carefully. |
Conversely, other drugs can reduce furosemide’s effectiveness. This can impact blood pressure control.
| Corticosteroids | Prednisone, Dexamethasone | Increased fluid retention, counteracting furosemide’s diuretic effect |
| Digoxin | Digoxin | Increased risk of digoxin toxicity due to electrolyte imbalances caused by furosemide |
This information is not exhaustive and does not replace professional medical advice. Always consult your doctor or pharmacist before making changes to your medication regimen. They can assess your individual needs and adjust your furosemide dosage accordingly to minimize the risk of adverse effects.
