Losartan: A Blood Pressure Medication and its Mechanism

Losartan is an angiotensin II receptor blocker (ARB). It lowers blood pressure by blocking the action of angiotensin II, a hormone that narrows blood vessels. This narrowing increases blood pressure.

Specifically, Losartan prevents angiotensin II from binding to its receptors (AT1 receptors) in blood vessel walls. This blockage stops the vasoconstricting effect of angiotensin II, allowing blood vessels to relax and widen. The result is decreased peripheral resistance and, consequently, lower blood pressure.

The medication is usually prescribed for hypertension and is also used to slow the progression of kidney disease in people with type 2 diabetes and high blood pressure. Its efficacy relies on its selective action on the AT1 receptor, minimizing potential side effects associated with non-selective ARBs. Remember to consult your doctor for dosage and usage instructions tailored to your specific health needs.

Important Note: Losartan can cause side effects, such as dizziness, fatigue, and changes in potassium levels. Always inform your physician about all medications you are taking, including over-the-counter drugs and supplements, before starting Losartan treatment. They can help manage potential interactions and side effects.

Disclaimer: This information is for educational purposes only and does not constitute medical advice. Always consult with a healthcare professional for any health concerns or before making any decisions related to your health or treatment.