Prolonged prednisone use in horses frequently leads to serious side effects like laminitis, muscle wasting, increased susceptibility to infections, and behavioral changes such as increased aggression or anxiety. Monitor your horse closely for these symptoms during treatment.
Managing Long-Term Prednisone Use
To mitigate these risks, veterinarians often prescribe the lowest effective dose for the shortest possible duration. Slow tapering of the medication is crucial to prevent sudden withdrawal symptoms. Regular blood tests monitor organ function, particularly liver and kidney health. Dietary adjustments, including increased fiber for gut health and protein to combat muscle loss, may also be recommended.
Alternatives to Prednisone
Non-Steroidal Anti-Inflammatory Drugs (NSAIDs): Phenylbutazone and flunixin meglumine offer pain relief and anti-inflammatory effects with fewer long-term side effects than prednisone, though they carry their own risks (e. g., gastric ulcers). Always consult your veterinarian before using NSAIDs.
Polysulfated glycosaminoglycans (PSGAGs): These drugs aid in cartilage repair and can be useful in managing conditions like osteoarthritis, sometimes reducing the need for prednisone. Their effect is often slower than prednisone’s immediate impact.
Other Therapeutic Options
Specific treatment depends entirely on the underlying condition. For instance, addressing underlying infections with antibiotics or treating allergic reactions with antihistamines can decrease reliance on prednisone. Your veterinarian will develop a tailored plan addressing your horse’s specific needs. Regular veterinary check-ups are paramount to effectively manage your horse’s health.


