Levofloxacin, a fluoroquinolone antibiotic, treats bacterial sinus infections when other antibiotics fail or aren’t suitable. Doctors typically prescribe it for acute bacterial sinusitis that hasn’t responded to first-line treatments like amoxicillin.
Specific situations warranting levofloxacin include severe sinusitis with complications, such as orbital cellulitis (infection behind the eye) or meningitis. A history of penicillin allergy may also lead a doctor to choose this antibiotic. Suspected infections caused by antibiotic-resistant bacteria are another crucial indicator for its use.
Your doctor will consider factors like the severity of your infection, your medical history (including allergies), and the results of any diagnostic tests (e. g., sinus X-rays or CT scans) before prescribing levofloxacin. They’ll assess whether the potential benefits outweigh the possible side effects.
Remember, levofloxacin is a powerful antibiotic with potential side effects. Always discuss your treatment options openly with your doctor. Self-medicating is dangerous; always seek professional medical advice for sinus infections.


