Always inform your doctor about all medications you’re taking, including over-the-counter drugs, herbal supplements, and recreational drugs. This includes nitrates (found in some heart medications), alpha-blockers (used for high blood pressure or prostate problems), and antifungal medications like ketoconazole or itraconazole. Combining Tadalafil with these can cause a dangerous drop in blood pressure.
Specific Medication Interactions
Combining Tadalafil with certain medications can lead to significant side effects. Below is a table highlighting some key interactions:
| Nitrates | Nitroglycerin, isosorbide mononitrate | Severe hypotension (dangerously low blood pressure) |
| Alpha-blockers | Terazosin, Doxazosin | Increased risk of dizziness and fainting |
| CYP3A4 Inhibitors | Ketoconazole, Itraconazole, Erythromycin | Increased Tadalafil levels, potentially leading to enhanced side effects |
| Ritonavir (HIV protease inhibitor) | Ritonavir | Increased Tadalafil levels, potentially leading to enhanced side effects |
Substances to Avoid
Grapefruit juice inhibits the metabolism of Tadalafil, leading to higher blood levels and increased risk of side effects. Avoid grapefruit juice while using Tadalafil. Alcohol can also enhance Tadalafil’s side effects, particularly dizziness and lightheadedness. Moderate alcohol consumption should be considered, and it’s always best to consult your physician before combining any medications, including Tadalafil, with alcohol.
Consult Your Doctor
This information isn’t exhaustive. Always consult your doctor or pharmacist before taking Tadalafil, especially if you have underlying health conditions or are taking other medications. They can provide personalized advice and assess potential risks.
