Doxycycline targets the bacteria responsible for most cases of non-gonococcal urethritis (NGU). It’s a broad-spectrum antibiotic, meaning it’s effective against a wide range of bacteria.
Mechanism of Action
Doxycycline inhibits bacterial protein synthesis. Specifically, it binds to the 30S ribosomal subunit of bacteria, preventing the addition of amino acids to the growing polypeptide chain. This halts bacterial growth and ultimately kills the bacteria.
Specific Bacteria Targeted
- Chlamydia trachomatis: A common cause of NGU, doxycycline effectively inhibits its growth and reproduction. Mycoplasma genitalium: Another frequent NGU culprit, doxycycline also disrupts its protein synthesis. Ureaplasma urealyticum: While less frequently the sole cause of NGU, doxycycline can still suppress this bacteria’s activity.
Dosage and Administration
The recommended dosage and duration of treatment vary depending on the specific infection and your doctor’s assessment. Always follow your healthcare provider’s instructions precisely. Typically, a course involves taking doxycycline twice daily for a specific period.
Important Considerations
Complete the entire course of antibiotics, even if symptoms improve. Stopping early can lead to treatment failure and antibiotic resistance. Inform your doctor about any allergies or medical conditions before starting treatment. Doxycycline can have side effects. Common ones include nausea, vomiting, diarrhea, and photosensitivity. Discuss any concerns with your doctor. Practice safe sex to minimize the risk of reinfection or transmission to partners.
Partner Treatment
It’s crucial for sexual partners to be tested and treated simultaneously to prevent reinfection and further spread.
