Check CVS’s weekly ad or their website for current sales and coupons. These promotions significantly impact the final price.
Store Location and Time of Year
Benadryl prices vary slightly depending on the specific CVS location. Rural stores may have higher prices than urban locations due to differing operating costs. Seasonal demand, especially during allergy season, can also affect prices; expect higher prices during peak allergy times.
Product Formulation and Size
The cost differs between Benadryl products. Liquid formulations, tablets, capsules, and even the package size (e. g., 24-count vs. 50-count) directly influence the price. Larger packages generally offer a lower per-unit cost.
Generic vs. Brand Name
Generic diphenhydramine (the active ingredient in Benadryl) is typically much cheaper than the brand-name Benadryl. Choosing a generic option can lead to considerable savings.
CVS Membership Programs
CVS offers various membership programs, like ExtraCare, that provide discounts and rewards. Enrolling in a program can lower the cost of Benadryl and other purchases. Check the details of your program for potential savings.
Payment Methods
Some payment methods might offer additional discounts or cashback rewards, further lowering the final cost.
Price Comparison Table
| Brand-Name Benadryl (24 ct tablets) | $8 – $12 | Price fluctuates with sales |
| Generic Diphenhydramine (24 ct tablets) | $4 – $7 | Significantly cheaper alternative |
| Benadryl Liquid (4 oz) | $6 – $10 | Price varies by size and formulation |
Remember to always check the CVS website or app for the most up-to-date pricing information. Using price comparison tools online can also help you find the best deals.


