Carprofen can interact negatively with other medications, so always inform your veterinarian about all medications your pet is currently taking, including supplements and over-the-counter drugs. This includes NSAIDs (like ibuprofen or naproxen which are toxic to pets), corticosteroids, anticoagulants (blood thinners), and aminoglycoside antibiotics.
Concurrent use with other NSAIDs increases the risk of gastrointestinal ulcers and kidney problems. Combining carprofen with drugs that affect kidney function, such as certain diuretics, may also worsen kidney damage.
Avoid using carprofen in pets with pre-existing liver or kidney disease, active gastrointestinal ulcers, or bleeding disorders. Pregnancy and lactation are also contraindications.
| NSAIDs (Ibuprofen, Naproxen etc.) | Increased risk of gastrointestinal ulcers and kidney damage | Avoid concurrent use. |
| Corticosteroids | Increased risk of gastrointestinal ulcers | Monitor closely for signs of gastrointestinal upset. |
| Anticoagulants | Increased bleeding risk | Careful monitoring of clotting times is required. |
| Aminoglycoside Antibiotics | Increased risk of kidney damage | Closely monitor kidney function. |
| Diuretics | Potential for worsening kidney function | Monitor hydration and kidney function closely. |
Always follow your veterinarian’s instructions regarding dosage and administration. If you observe any unusual side effects, contact your veterinarian immediately.
