Prednisone and methotrexate carry specific contraindications. Avoid prednisone if you have a known allergy to corticosteroids or a history of severe fungal infections. Active tuberculosis, untreated infections, and recent live virus vaccinations also call for caution.
Methotrexate poses risks for those with severe liver or kidney disease, bone marrow suppression, significant gastrointestinal issues, or active peptic ulcers. Pregnant or breastfeeding women should absolutely avoid methotrexate. Similarly, avoid methotrexate if you’re allergic to it or have a history of serious allergic reactions to other folate antagonists.
Always discuss these medications with your doctor. They will assess your individual health history and circumstances to determine the safest treatment option for you. Open communication ensures the best possible outcome.
Remember, this information isn’t a substitute for professional medical advice. Consult your physician before starting any medication.
