Amoxicillin treats a wide range of bacterial infections, including ear infections (otitis media), sinusitis, bronchitis, pneumonia, and urinary tract infections. It’s also frequently used for skin infections and strep throat. Doctors often choose amoxicillin as a first-line treatment due to its good oral bioavailability and relatively low cost.
Amoxicillin vs. Other Penicillins
Compared to penicillin V, amoxicillin boasts superior absorption after oral administration, leading to higher blood levels. This makes it more effective for some infections. Ampicillin, another penicillin, has a broader spectrum of activity against certain bacteria, particularly gram-negative organisms, but it’s associated with more gastrointestinal side effects than amoxicillin. Amoxicillin/clavulanate (Augmentin) combines amoxicillin with clavulanic acid to overcome resistance caused by beta-lactamases, enzymes that some bacteria produce to inactivate penicillins. This combination extends its effectiveness against a wider range of bacteria resistant to amoxicillin alone. The choice between these penicillins depends on the specific infection, the patient’s history, and the susceptibility of the bacteria involved.
For instance, if a patient has a penicillin allergy, alternative antibiotics are needed. Consider factors like age, allergies, and potential drug interactions when selecting the appropriate penicillin.


