Zyprexa (olanzapine) isn’t FDA-approved for anxiety. However, its sedative properties sometimes lead doctors to prescribe it off-label for managing severe anxiety, particularly when other treatments haven’t worked. This is usually considered only for individuals with very resistant anxiety that significantly impacts their daily life.
Doctors might consider this approach if you experience anxiety alongside other conditions, such as bipolar disorder or schizophrenia, where Zyprexa is a standard treatment. The calming effect can help manage anxiety symptoms as a secondary benefit.
It’s crucial to understand that this is an off-label use, meaning the drug’s efficacy and safety for anxiety haven’t been extensively studied in clinical trials. Potential side effects, including weight gain, drowsiness, and metabolic changes, must be carefully considered.
| Reduced anxiety symptoms | Weight gain |
| Improved sleep | Drowsiness |
| Reduced agitation | Metabolic changes (increased blood sugar, cholesterol) |
Regular monitoring of your weight, blood pressure, and blood sugar levels is necessary if you’re taking Zyprexa for anxiety. Open communication with your psychiatrist is paramount; they can assess your progress, adjust dosage, or explore alternative treatments if needed. Remember, you should never start or stop taking medication without your doctor’s guidance.


