Acetazolamide uptodate

Begin by understanding acetazolamide’s primary action: inhibiting carbonic anhydrase. This directly impacts fluid balance, making it highly effective for managing altitude sickness and glaucoma.

Dosage adjustments are crucial. For altitude sickness prophylaxis, a low dose, started before ascent, is recommended. Glaucoma treatment often requires higher doses, carefully tailored to individual patient response and monitored by regular ophthalmological examinations. Always adhere to prescribed regimens.

Side effects, though common, are usually mild and transient. These may include paresthesias, metabolic acidosis, and renal stones. Patients should be aware of these possibilities and report any concerning symptoms to their physician immediately. Regular blood tests may be necessary to monitor electrolyte balance.

Contraindications include sulfa allergy and severe renal impairment. Careful consideration is also needed in patients with cirrhosis, respiratory acidosis, or Addison’s disease. Consult a medical professional before initiating treatment, especially if you have pre-existing medical conditions.

Remember: This information is for educational purposes only and should not replace professional medical advice. Always consult your doctor or pharmacist for personalized guidance and before making any decisions related to your health.